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小胃肠道间质瘤的诊断和治疗策略
  • ISSN号:1673-9752
  • 期刊名称:《中华消化外科杂志》
  • 时间:0
  • 分类:R735[医药卫生—肿瘤;医药卫生—临床医学]
  • 作者机构:[1]北京大学人民医院胃肠外科,100044
  • 相关基金:北京市自然科学基金(7112136)
中文摘要:

长期以来胃肠道间质瘤(GIST)的实际发病率常被低估。随着对这一疾病的认识和检查技术的进步,小GIST患者(直径〈5cm)的检出率逐年升高。该类患者多无明显临床症状,常在体格检查被意外发现。对于这类患者的诊断需要联合内镜和CT检查。在明确诊断的基础上,对直径〉/2cm的小GIST患者应积极行肿瘤的完整切除术,而目前腹腔镜手术逐渐成为治疗的标准术式。对于直径〈2cm的微小GIST,特别是微小胃间质瘤,目前的指南推荐可以行密切随访,有学者提倡内镜切除肿瘤。笔者认为应当谨慎鉴别小GIST恶性潜能而后选择个体化治疗策略。

英文摘要:

The actual incidence of gastrointestinal stro- real tumor (GIST) is underestimated. With the progression of awareness and development of examination methods, the detection rate of small GIST ( diameter 〈 5 cm) is increasing year by year. These patients always had no obvious clinical symptoms, and were often detected with small GIST in physical examination unexpectedly. Combination of endoscopic ultrasound and radiographic examination is helpful in detecting small GIST. Aggressive surgical complete resection should be considered in case of a definitive diagnosis. Laparoscopic resection is becoming the standard surgical treatment currently. For micro GIST (diameter 〈 2 cm), especially micro gastric stromal tumor, current guidelines recommend close observation. Some scholars advocate that endoscopic resection is feasible for the treatment of micro GIST, while we think that the efficacy of individualized treatment is better after identifying the potential malignancy of micro GIST.

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期刊信息
  • 《中华消化外科杂志》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中华医学会
  • 主编:
  • 地址:重庆沙坪坝区高滩岩30号
  • 邮编:400038
  • 邮箱:digsurg@263.net
  • 电话:023-68754655
  • 国际标准刊号:ISSN:1673-9752
  • 国内统一刊号:ISSN:11-5610/R
  • 邮发代号:78-117
  • 获奖情况:
  • 科技期刊论文统计源,中国科技核心期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,中国中国科技核心期刊,中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:8916