目的探讨老年轻度认知功解障碍者人格特征,为采取有效的预防措施提供科学依据。方法2008年,采用整群随机抽样方法在山西省太原市选取9个社区的老年人群中轻度认知功能障碍者(MCI)232例,按年龄、性别、文化程度进行1∶1配对的病例对照研究。采用Epi-Data和SPSS13.0软件进行单因素和多因素条件Logistic回归分析。结果单因素条件Logistic回归分析发现,卡特尔16种人格因素问卷(16PF)中的乐群(A)(χ^22.826,P=0.003)、恃强(E)(χ^211.581,P=0.000)、忧虑(O)(χ^22.409,P=0.001)、独立(Q2)(χ^20.351,P=0.046)、自律(Q3)(χ^20.173,P=0.001)在MCI组与对照组之间差异有统计学意义。多因素条件Logistic回归分析结果显示,16PF中恃强(E)(χ^234.920,P=0.000)、独立(Q2)(χ^24.168,P=0.041)、自律(Q3)(χ^26.560,P=0.010)在MCI组与对照组之间差异有统计学意义,并且16PF中的独立(Q2)(OR=0.050,95%CI=0.005-0.515)、自律(Q3)(OR=0.057,95%CI=0.009-0.407)是MCI的保护性因素,且独立并自律是轻度认知功能障碍的保护性因素(OR=0.059,95%CI=0.011-0.298)。结论16PF中恃强性是MCI的危险性因素。高独立性及高自律性为MCI的保护性因素,且高独立性并高自律性对MCI的影响分别存在主效应及联合作用效应。
Objective To explore the role of personality in mild cognitive impairment(MCI)and to provide a scientific evidence for taking effective preventive measures.Methods With random cluster sampling method,232 subjects with MCI and 232 controls matched by age,sex and education were selected from elder population in nine communities of Taiyuan in 2008.The single factor and the multi-factor condition logistic regression were performed with Epi-Data and SPSS13.0 software.Results The results of single factor condition logistic regression showed that there were significant differences between the MCI group and the control group in all factors of Cartel's 16 Peronality Factor Questionnaire(16PF) such as liveliness(A)(χ^2 2.826,P=0.003),aggressiveness(E)(χ^2 11.581,P=0.000),anxiety(O)(χ^22.409,P=0.001),independence(Q2)(χ^2 0.351,P=0.046)and perfectionism(Q3)(χ^20.173,P=0.001).The results of the multi-factor condition logistic regression analysis showed that there were significant differences in 16 PF's scores including aggressiveness(E)(χ^2 34.920,P=0.000),independence(Q2)(χ^24.168,P=0.041),perfectionism(Q3)(χ^2 6.560,P=0.010).Among factors of 16 PF,independence(Q2)(OR=0.050,95% CI=0.005~0.515),perfectionism(Q3)(OR=0.057,95%CI=0.009~0.407)were the independent protective factors of MCI.At the same time,the interaction of independence(Q2) and perfectionism(Q3) were identified as the independent preventive factors of MCI(OR=0.059,95% CI=0.011~0.298).Conclusion In factors of 16 PF,aggressiveness is the independent risk factor of MCI.Independence and perfectionism are the protection factors of MCI.High independence and high perfectionism in 16 PF factors have both independent role and interaction role on MCI.