目的评价3TMR对比增强全心冠状动脉成像(CE—CMRA)诊断冠状动脉有意义狭窄(≥50%)的诊断价值。方法顺序搜集53例拟诊冠心病患者行3TCE—CMRA,采用心电门控、呼吸导航和梯度回波序列,并加用非选择性反转恢复脉冲抑制心肌信号。增强采用钆贝葡胺注射液静脉缓慢注射,流率0.3ml/s。以X线冠状动脉造影结果作为参考标准,分别计算CE—CMRA诊断冠状动脉主要分支(9段划分法)和全部分支(15段划分法)有意义狭窄(≥50%)的诊断准确性。结果53例患者中,48例(90%)成功完成检查,平均扫描时间为(9.1±1.8)min。以冠状动脉9段划分标准,3TCE-CMRA在节段水平诊断有意义狭窄的敏感性和特异性分别为92.2%(59/64)和91.5%(324/354)。以冠状动脉15段划分标准,其敏感性和特异性则分别为82.4%(70/85)和86.1%(446/518)。结论3TCE-CMRA诊断冠状动脉主要分支有意义狭窄具有较高敏感性和特异性。对冠状动脉较小分支,3TCE-CMRA的诊断准确性仍有一定的限度。
Objective To evaluate the diagnostic performance of 3 T contrast-enhanced whole-heart coronary MR angiography (CE-CMRA) in patients with suspected coronary artery disease. Methods 3 T CE-CMRA was performed in 53 consecutive patients. An ECG-triggered, navigator-gated, inversion-recovery prepared, segmented gradient-echo sequence was used to acquire CE-CMRA with slow infusion of 0. 2 mmol/kg Gd-BOPTA. Using X-ray angiography as the reference, the diagnostic accuracy of the CE- CMRA in detecting significant stenosis (≥50% ) was assessed based on the 9 segments of coronary artery main branches and on the 15 segments of the coronary artery, respectively. Results The CE-CMRA examinations was successfully completed in 48 patients ( 90% ). The average acquisition time of the scan was (9. 1±1. 8 ) min. The sensitivity and specificity of CE-CMRA for detecting significant stenoses based on the 9 segments and 15 segments were 92. 2% (59/64)and 91.5% (324/354) ,82.4% (70/85) and 86. 1% (446/518) ,respectively. Conclusion 3 T CE-CMRA allows for accurate detection of coronary artery stenosis of the main coronary artery branches with high sensitivity and specificity, but is still limited in small coronary branches.