中文摘要：

取代苯乙烯1与KHS05在手性催化剂2存在的条件下反应，生成1-芳基环氧化物3，3与1H-1，2,4-三唑在固体碳酸钾催化下作用，得到手性的1-芳基-2-（1H-1，2，4-三唑-1-基）乙醇衍生物4-部分4对甾醇14α-脱甲基化酶表现出强结合作用．

英文摘要：

Substituted styrene 1 was reacted with KHSO5 in the presence of the chiral catalyst 2 to give aryloxiranes 3, which were subsequently treated with 1H-1,2,4-triazole and potassium carbonate to generate enantioriched 1-aryl-2-（1H-1,2,4-triazol-1-yl）ethanols 4. Some of the triazoles 4 exhibited strong binding interactions with the cytochrome P450-dependent sterol 14α-demethylase （CYP51）.