中文摘要：

目的东南沿海地区是肾综合征出血热（HFRS）的主要疫区 了解该地区HFRS自然疫源地的地理景观结构,分析流行特征、为预防措施提供理论依据。方法根据以往资料和疫区类型选择14个地区应用地理景观和血清流行病学方法进行调查,分析该病的流行特征。结果该地区景观特点是以平原和丘陵为主,多湿润,位于多水带,属亚热带和温带气候,具有广阔的农作物,为HFRS主要宿主动物提供了良好的栖息繁殖和食物条件。黑线姬鼠和褐家鼠是HFRS的主要宿主动物和传染源,数量多,带毒率高 14个出血热疫区共检查鼠形动物4 386只,出血热抗原阳性267只,阳性率为5.1% 出血热抗体阳性364只,阳性率8.3%。近5年来该地区HFRS发病率较2000年以前有所上升。结论东南沿海地区仍是HFRS的主要疫区。

英文摘要：

Objective To understand the geographical landscape structure of epidemic area of hemorrhagic fever with renal syndrome（HFRS） and to analysis the characteristics of the epidemic in order to provide a theoretical basis for preventive measures of the disease. Methods According to data of HFRS epidemic, 14 areas were chosen and the investigation was carried out with an application of geographical landscape and seroepidemiological survey to analyze the epidemic characteristic of the disease. Results The local landscape characteristic was mally hills and plains with subtropical and temperate climate and the environment provided a favourable condition for the host animal of HFRS. Apodemus agrarius and Rattus norvegicus were principal animal reservoir of HFRS. Among 4386 murine animals screend ,267 （5.1% ） were HFRS antigen positive and 364（8. 3% ） were HFRS antibody positive. The incidence rate of HFRS increased in the latest five years com- pared with that of in the year 2000. Conclusion The southeast coastal area is still an important hemorrhagic fever epidemic area and further detection and analysis are required.