中文摘要：

假基因是指基因组中与正常编码蛋白基因序列相似,但缺乏明确生理功能的基因序列.近年来研究表明,许多假基因在肿瘤中能够活跃转录并翻译蛋白,在遗传水平、转录水平和转录后水平调控基因的表达活性,然而其功能及作用机制还有待进一步探索.

英文摘要：

Pseudogenes are sequences in the genome that are similar to the gene sequences which can encode proteins normally,but are lack of a clear physiological function.Recently,researches show that pseudogenes can transcribe and translate actively,and can regulate the expression of genes at the genetical,transcriptional and post-transcriptional levels.However,their effects and mechanisms remain to be clarified.