中文摘要：

金鸡纳碱衍生的季铵盐催化二苯亚甲基甘氨酸叔丁酯与α,β不饱和酮的不对称Michael加成反应,常温条件下取得99%的产率,达到57%的对映选择性以及高于20∶1的区域选择性.合成了7个未见文献报道的取代的甘氨酸衍生物,其结构得到1H NMR确证.

英文摘要：

The asymmetric Michael addition reaction of N-（benzophenone） glycine tert-butyl ester with α,β-Unsaturated Ketones catalyticed by cinchona-derived quaternary ammonium salts afforded 99% yield and 57% enantioselectivity with up to 20：1 regioselectivity in room temperature.we synthesized seven substituted glycine derivatives which have not been reported.All the structures have been characterized by 1H NMR and some by 13C NMR.