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Engineering a Cell-Surface Aptamer Circuit for Targeted and Amplified Photodynamic Cancer Therapy
ISSN号:1936-0851
期刊名称:ACS Nano
时间:2013.2.11
页码:2312-2319
相关项目:化学生物传感的分析化学基础研究
作者:
Da Han, Guizhi Zhu, Cuichen Wu, Zhi Zhu,|Tao Chen, Xiaobing Zhang, and Weihong Tan*|
同期刊论文项目
化学生物传感的分析化学基础研究
期刊论文 304
同项目期刊论文
Noncanonical Self-Assembly of Multifunctional DNA Nanoflowers for Biomedical Applications
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Engineering and applications of DNA-grafted polymer materials
Using Aptamers for Cancer Biomarker Discovery
A simple and pH-independent and ultrasensitive fluorescent probe for the rapid detection of Hg2+
A Targeted, Self-Delivered, and Photocontrolled Molecular Beacon for mRNA Detection in Living Cells
Development of a highly robust solid phase microextraction fiber based on crosslinked methyl methacr
Sensitive Electrochemical Aptasensor by Coupling “Signal-on” and “Signal-off” Strategies
Simultaneous electrochemical detection of ascorbic acid, dopamine and uric acid based on nitrogen do
Sensitive electrochemical detection of hydroxyl radical based on MBs-DNA-AgNPs nanocomposite
A Controlled-Release Nanocarrier with Extracellular pH Value Driven Tumor Targeting and Translocatio
Recent Advances in Optical Imaging with Anisotropic Plasmonic Nanoparticles
A flexible trilineardecomposition algorithm for three-way calibration based on the trilinear compone
Noncovalent assembly of reduced graphene oxideand alkyl-grafted mesoporous silica: an effective drug
Targeted Intracellular Controlled Drug Delivery and Tumor Therapy through in Situ Forming Ag Nanogat
Localizableand Photoactivatable Fluorophore for Spatiotemporal Two-Photon Bioimaging
DNA-templated in situ growth of silver nanoparticles on mesoporous silica nanospheres for smart intr
Rapid andsimultaneous determination of five vinca alkaloids in catharanthus roseus andhuman serum us
A combination of positive dielectrophoresis driven on-line enrichment and aptamer-fluorescent silica
Redox-responsive degradable honeycomb manganese oxide nanostructures aseffective nanocarriers for in
Single-base mismatch discrimination by T7 exonuclease with target cyclic amplification detection
Ultrasensitive Detection of Single Nucleotide Polymorphism inHuman Mitochondrial DNA Utilizing Ion-M
Magnetic graphene oxide modified with choline chloride-based deep eutectic solvent for the solid-pha
Ultrasensitive Electrochemical Detection of Nucleic Acids Based on the Dual-Signaling Electrochemica
DNA “Nano-Claw”:Logic-Based Autonomous Cancer Targeting and Therapy
Enzymatic cleavage and mass amplification strategy for small molecule detection using aptamer-based
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Magnetic-graphene based molecularly imprinted polymer nanocomposite for the recognition of bovine he
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Using DNA Aptamer Probe for Immunostaining of Cancer Frozen Tissues
Poly(thymine)-Templated Copper Nanoparticles as a Fluorescent Indicator for Hydrogen Peroxide and Ox
Analysis of perfluorooctane sulfonate and perfluorooctanoic acid with a mixed-mode coating-based sol
Label-Free and Turn-on Aptamer Strategy for Cancer Cells Detection Based on a DNA−Silver N
A New Dual-Signalling Electrochemical Sensing Strategy Based on Competitive Host–Guest Int
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Remote-Controlled Release of DNA in Living Cells via Simultaneous Light and Host–Guest Mediations
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Two novel zeolitic imidazolate frameworks (ZIFs) as sorbents for solid-phase extraction (SPE) of pol
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Enhanced nonenzymatic sensing of hydrogen peroxide released from living cells based on Fe3O4/self-re
The adenine DNA self-assembled of pH- and near-infrared-responsive gold nanorods vehicle for chemoth
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Co-loading of coralyne and indocyanine green into adenine DNA-functionalized mesoporous silica nanop
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Amplified electrochemical detection of protein kinase activity based on gold nanoparticles/multi-wal
Remote-controlled drug release from graphene oxide-capped mesoporous silica to cancer cells by photo
Label-free activatable aptamer probe for colorimetric detection of cancer cells based on binding-tri
Visual and Portable Strategy for Copper(II) Detection Based on a Striplike Poly(Thymine)-Caged and M
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Concatemeric dsDNA-Templated Copper Nanoparticles Strategy with Improved Sensitivity and Stability B
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Inorganic fluorescent nanoprobes for cellular and subcellular imaging: status and challenges
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pH-responsive polymer/mesoporous silica nano-container through an acid cleavable linker for intracel
Cell Membrane-Anchored Biosensors for Real-Time Monitoring of the Cellular Microenvironment
Isothermal Nucleic Acid Amplification Strategy by Cyclic Enzymatic Repairing for Highly Sensitive Mi
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Direct Imaging of Transmembrane Dynamics of Single Nanoparticles with Dark?eld Microscopy: Improved
High-Throughput Sul?de Sensing with Colorimetric Analysis of Single Au?Ag Core?Shell Nanoparticles
Color Di?erence Ampli?cation between Gold Nanoparticles in Colorimetric Analysis with Actively Contr
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Reversible Phase Transfer of Nanoparticles Based on Photoswitchable Host-Guest Chemistry
Facile Surface Functionalization of Hydrophobic Magnetic Nanoparticles
DNA “Nano-Claw”: Logic-Based Autonomous Cancer Targeting and Therapy
Molecular Engineering of a TBET-Based Two-Photon Fluorescent Probe for Ratiometric Imaging of Living
Activatable Fluorescence/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet–Aptamer Nano
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Gold nanorod-photosensitizer conjugate with extracellular pH-driven tumor targeting ability for phot
Aptamer-conjugated nanomaterials for specific cancer cell recognition and targeted cancer therapy
A ratiometric electrochemical biosensor for sensitive detection of Hg2+ based on thymine-Hg2+-thymin
Nanomaterials as signal amplification elements in DNA-based electrochemical sensing
Simultaneous electrochemical determination of hydroquinone, catechol and resorcinol at nitrogen dope
Highly-selective electrochemical determination of catechol based on 3-aminophenylboronic acid-3,4,9,
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Intelligent layered nanoflare: “lab-on-a nanoparticle” for multiple DNA logic gate operations and ef
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Quantitative study of state switching in proteins using a single probe combined with trilinear decom
Magnetic solid-phase extraction of proteins based on hydroxy functional ionic liquid-modified magnet
Rhodamine-based fluorescent probe for direct bioimaging of lysosomel pH changes
An efficient ratiometric fluorescent excimer probe for hypochlorite based on a cofacial xanthene bri
An aggregated perylene-based broad-spectrum, efficient and label-free quencher for multiplexed fluor
Chemometrics-enhanced high performance liquid chromatography -diode array detection strategy for sim
Simultaneous determination of phenolic antioxidantsinedible vegetableoils by HPLC-FLD assisted withs
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Entropy beacon: a hairpin-free DNA amplification strategy forefficient detection of nucleic acids
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Efficient Two-Photon Fluorescent Probe for NitroreductaseDetection and Hypoxia Imaging in Tumor Cell
Nucleic Acid Based Logical Systems
Functional DNA-Containing Nanomaterials: Cellular Applications in Biosensing, Imaging, and Targeted
Direct Visualization of Walking Motions of Photocontrolled Nanomachine on the DNA Nanostructure
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Sensitive and Rapid Detection of Endogenous Hydrogen Sulfide Distributing in Different Mouse Viscera
Simultaneous determination of naphazoline and pyridoxine in eye drops using excitation–emission matr
Nuclease-resistant synthetic drug-DNA adducts: programmable drug-DNA conjugation for targeted antica
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Chemometrics-assisted determination of amiloride and triamterene in biological fluids with overlappe
A Nonenzymatic Hairpin DNA Cascade Reaction Provides High Signal Gain of mRNA Imaging inside Live C
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Silver Nanoparticle Gated, Mesoporous Silica Coated Gold Nanorods (AuNR@MS@AgNPs): Low Premature Rel
Electrostatic nucleic acid nanoassembly enables hybridization chain reaction in living cells for ult
Nucleic acid amplification-based methods formicroRNA detection
Split aptamer mediated endonuclease amplification for small-molecule detection
Hemicyanine-based High Resolution Ratiometric near-Infrared Fluorescent Probe for Monitoring pH Chan
Iodide-Responsive Cu?Au Nanoparticle-Based Colorimetric Platform for Ultrasensitive Detection of Tar
Masking agent-free and channel-switch-mode simultaneous sensing of Fe3+ and Hg2+ using dual-excitati
Preparation of magnetic chitosan and graphene oxide-functional guanidinium ionic liquid composite fo
A ratiometric electrochemical biosensor for sensitive detection of Hg2+ based on thymine–Hg2+–thymin
A label-free electrochemical strategy for highly sensitive methyltransferase activity assays
PlatinumNanoparticles Encapsulated in Nitrogen-Doped Mesoporous Carbonsas Methanol-Tolerant Oxygen R
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双牺牲模板法制备一维管状Pt-Mn3O4-C复合物及其优越的甲醇电催化氧化性能
Nucleic acid-mimicking coordination polymer for label-free fluorescent activity assay of histone ace
A universal platform for building molecular logic circuits based on a reconfigurable three dimension
Fast quantitative analysis of four tyrosine kinase inhibitors in different human plasma samples usin
DNA Aptamer Selected against Pancreatic Ductal Adenocarcinoma for in vivo Imaging and Clinical Tissu
Studyof the Function of G-Rich Aptamers Selected for Lung Adenocarcinoma
Programmed packaging of mesoporous silica nanocarriers for matrixmetalloprotease 2-triggered tumor t
A highly sensitive electrochemiluminescence assay for protein kinase based on double-quenching of gr
Glutathione-Mediated Degradation of Surface-Capped MnO 2 for Drug Release from Mesoporous Silica Nan
Adenosine-5-Triphosphate Aptamer Containing Triple-Helix DNA Capped Mesoporous Silica Nanoparticles
Optical analysis of biological hydrogen sulphide:an overview of recent advancements
Fluorescent Gold Nanodots Based Sensor Array for Proteins Discrimination
Phosphorylation-Mediated Assembly of a Semisynthetic Fluorescent Protein for Label-Free Detection of
Multi-targeted interference-free determination of ten β-blockers in human urine and plasma samples b
Lateral epitaxial growth of two-dimensional layered semiconductor heterojunctions
Nucleic Acid Aptamers for Living Cell Analysis
A pH-responsive polymer/mesoporous silica nano-container linked through an acid cleavable linker for
Building a Multifunctional Aptamer-Based DNA Nanoassembly for Targeted Cancer Therapy
Targeted Bioimaging and Photodynamic Therapy Nanoplatform Using an Aptamer-Guided G-Quadruplex DNA C
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Annexin-V modified QCM sensor for the label-free and sensitive detection of early stage apoptosis
A new strategy based on cholesterol-functionalized iron oxide magnetic nanoparticles for determinati
A superquenched DNAzyme-perylene complex: a convenient, universal and low-background strategy for fl
DNA Micelle Flares for Intracellular mRNA Imaging and Gene Therapy
DNAzyme-Based Probes for Telomerase Detection in Early-Stage Cancer Diagnosis
Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer
Building Fluorescent DNA Nanodevices on Target Living Cell Surfaces
Multicolor Fluorescent Biosensor for Multiplexed Detection of DNA
DNA Nanoflowers for Multiplexed Cellular Imaging and Traceable Targeted Drug Delivery
A highly sensitive and reductant-resistant fluorescent probe for nitroxyl in aqueous solution and se
A rhodamine-appended water-soluble conjugated polymer: an efficient ratiometric fluorescence sensing
Programmable and Multiparameter DNA-Based Logic Platform For Cancer Recognition and Targeted Therapy
Single Nanoparticle to 3D Supercage: Framing for an Artificial Enzyme System
Preparation and biomedical applications of programmable and multifunctional DNA nanoflowers
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Selective Colorimetric Detection of Hydrogen Sulfide Based on Primary Amine-Active Ester Cross-Linki
Quantitative investigation of the dynamic interaction of human serum albumin with procaine using a m
Screening of DNA Aptamers against Myoglobin Using a Positive and Negative Selection Units Integrated
Aptamer/target binding-induced triple helix forming for signal-on electrochemica lbiosensing
Magnetic multiwall carbon nanotubes modified with dual hydroxy functional ionic liquid for the solid
DNA Aptamer-Mediated Cell Targeting
Selective Tracking of Lysosomal Cu2+ Ions Using Simultaneous Target- and Location-Activated Fluoresc
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DNA-templated in situ growth of AgNPs on SWNTs: a new approach for highly sensitive SERS assay of mi
A Smart DNAzyme–MnO2 Nanosystem for Efficient Gene Silencing
Self-assemblyof DNA Nanohydrogels with Controllable Size and Stimuli-Responsive Property for Targete
Evolution of Functional Six-Nucleotide DNA
Multiple Functional Nanoprobe for Contrast-Enhanced Bimodal Cellular Imaging and Targeted Therapy
DLISA:A DNAzyme-Based ELISA for Protein Enzyme-Free Immunoassay of Multiple Analytes
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三线性分解方法用于光谱数据中背景漂移的扣除
“金标银染”放大技术的羟基自由基灵敏检测
Pt纳米颗粒在聚二甲基二烯丙基氯化铵功能化碳纳米管上的自发沉积及其对甲醇的电催化氧化性能(英文)
核酸适配体靶向药物的“导航仪”研究
Self-assembled multifunctional DNA nanoflowers for the circumvention of multidrug resistance in targeted anticancer drug delivery
Fabrication of ultrathin Zn(OH)2 nanosheets as drug carriers
Background-free three-dimensional selective imaging of anisotropic plasmonic nanoparticles