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应用欧洲五维生活质量量表评价突发性聋疗效

ISSN号：1001-1781
期刊名称：《临床耳鼻咽喉头颈外科杂志》
时间：0
分类：R764.43[医药卫生—耳鼻咽喉科;医药卫生—临床医学]
作者机构：解放军总医院耳鼻咽喉头颈外科,北京100853
相关基金：国家“973”重大科研计划（No：2012CB967900）;中国博士后科学基金面上项目（No：2013M542520）

关键词：欧洲五维生活质量量表, 生活质量, 突发性聋, EQ-5D, quality of life, idiopathic sudden sensorineural hearing loss

中文摘要：

[摘要]目的：应用欧洲五维生活质量量表（中文版1．O）（EQ-5D-3L）对突发性聋患者的生活质量进行评估，探讨EQ-5D-3L对突发性聋患者评估的可行性。方法：回顾性分析。随机抽取在我科就诊的突发性聋患者60例，在一次疗程前和疗程后分别给予EQ-5D-3I。对患者进行评估。使用配对资料的Wilcoxon符号秩和检验分析治疗前后5个方面的评价结果，使用成组配对t检验分析治疗前后的VAS评分。完善相关听力检查，并记录患者是否伴发耳闷、眩晕、呕吐等不适。记录以治疗前后听力检查情况及伴发症状是否改善，使用一致性分析对量表的相关维度进行可靠性评价。结果：60例患者的问卷都完整填写。统计患者在行动能力、自我照顾能力、日常活动能力、疼痛或不适、焦虑或抑郁等方面在治疗前后的差异，结果显示患者在治疗前后疼痛或不适、焦虑或抑郁有改善（P〈0．05），而行动能力、自我照顾能力、日常活动能力的前后差异无统计学意义（P〉0．05）。伴随症状和疼痛或不适维度具有较好的可靠性，总体疗效情况与VAS自评得分具有极好的一致性。结论：EQ-5D能够显示突发性聋患者在不适、焦虑等情况的改变。其得分评价显示主观得分与客观实际情况的相符合。EQ-5D量表可以作为突发性聋患者治疗效果的评估方式之一。

英文摘要：

Objective：To investigate the applicability of EuroQol 5-Dimension 3-Level questionnaire（Chinese Version1.0）（EQ-5D-3L）in the assessment of life quality of patients with idopathic sudden hearing loss.Method：In this retrospect study,the EQ-5D-3 Lwas assigned to 60 patients with idopathic sudden hearing loss before and after drug therapy.Audiometry examinations were undertaken and concomitant symptoms were recorded.A Wilcoxon rank sum test was applicated to the comparisons of results of EQ-5D-3 Lbefore and after the treatment,a t-test for results of EQ-VAS and a Kappa measurement for the consistency of certain dimension correlated with the symptoms.Result：Sixty patients completed the five questions and visual analog scale of the EQ-5D.A statistically significant changes of pain/discomfort,anxiety/depression before and after the treatment were observed（P〈0.05）.The domains of mobility,self-care and usual activities did not show statistically significant different（P〉0.05）.The dimension of pain/discomfort was in agreement with the concomitant symptoms.And the result of EQ-VAS was in agreement with the therapeutic outcome.Conclusion：It is suitable for the EQ-5 Dto be a general health measure with sensitivity to clinical change in idiopathic sudden sensorineural hearing loss,which monitors the patients′outcomes.

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