中文摘要：

砷及其化合物是国际癌症研究机构确认的人类致癌物。砷的广泛分布及其对机体造成许多不良影响,使得砷中毒已然成为全球性公共卫生问题。笔者综述了长期砷暴露引起机体多系统的严重损害,可造成肝脏、肾脏、肺脏、皮肤、神经系统及免疫系统的相关疾病甚至癌症,并对研究长期砷暴露对机体损伤的机制进行了展望。

英文摘要：

Arsenic and its compounds have been identified as a human carcinogen by International Agency for Research on Cancer （IARC）. Since wide distribution of arsenic and its many adverse effects on the body,arsenism has become a global public health problem. In the present paper,the recent studies were reviewed on the long-term arsenic exposure-induced serious damage of liver,kidney, lung, skin, nervous system and immune system and the related tumors.