【目的】探讨良性前列腺增生(BPH)与动脉硬化症的可能关系及BPH的可能病因。【方法】统计分析200例良性前列腺肥大(BPE)患者中动脉硬化症发生的比例,并以使用过药物治疗动脉硬化症且未使用过治疗前列腺药物者为观察组;与未使用过药物治疗动脉硬化症且未使用过治疗前列腺的药物者为对照组。比较两组需药物或手术治疗的BPH例数有无差异。【结果】200例BPE患者中,伴有动脉硬化症的196倒(98%);观察组中需药物或手术治疗BPH患者31例(15.5%)较对照组中42例(21.0%)明显减少(P=0.003)。【结论】BPH的发生发展与动脉硬化症有着极其密切的关系,动脉硬化症可能是BPH的一个重要病因.
[Objective]To investigate the possible relationship between benign prostatic hyperplasia and atherosclerosis, and the possible etiology of benign prostatic hyperplasia, [Methods]Retrospective study was done on the clinical data of 200 patients with benign prostatic enlargement, and the ratio of benign prostatic enlargement accompanied with atherosclerosis in the 200 patients was obtained. Two hundred patients were divided into observational group, treated with the medicine to atherosclerosis but not to benign prostatic hyper- plasia(BPH), and contrasted group, never treated with the medicine to atherosclerosis and BPH, Chi-square test was used to analyse the BPH patients needing medicine or surgery treatment in the two groups, [Results] In the 200 patients, there were 196 patients (98 % ) accompanied with atherosclerosis, far more than 4 (2 %) without atherosclerosis. And in the observational group, there were 31 patients(15. 5 %) treated with medicine or surgery for benign prostatic hyperplasia. Compared with the contrasted group(42 patients, 21.0%), the incidence of observational group (31 patients, 15.5 %) in which the patients of BPH were treated with medicine or surgery was obviously decreased( P = 0. 003), [Conclusions] There is a close relationship between BPH and atherosclerosis, Atherosclerosis maybe is its possible important etiology.