中文摘要：

在（R,R）-RuCl（Fsdpen）（p-cymene）催化下进行了4-芳基-2,4-二羰基丁酸酯的不对称氢转移反应研究。考察了溶剂和温度对反应的影响;并以DMF为溶剂在0℃时进行了7种4-芳基-2,4-二羰基丁酸酯的不对称转移氢化（ATH）反应,得到高达85%产率和96%ee的反应产物;同时探索了（2R,4S）-α-羟基-γ-苯基-丁内酯的不对称合成。

英文摘要：

The probe of the asymmetric transfer hydrogenation（ ATH） of a series of γ-aryl-α,γ-dioxo-butyric acid esters had been conducted with（ R,R）-Ru Cl（ Fsdpen）（ p-cymene） as catalyst.The reaction conditions were optimized and seven substrates＇ ATH proceeded smoothly.Up to 85%chemical yields and 96%ee were obtained.Simultaneously,the synthesis of a trans-2,4-disubstituted butyrolactone could also be achieved with a yield of 45%.