中文摘要：

目的观察血栓通对颅外伤合并多发性肋骨骨折患者的临床疗效。方法 66例颅外伤合并多发性肋骨骨折患者随机分为对照组33例和试验组33例。2组均实施手术纠正及持续吸氧、降颅压、神经营养支持、纠正水电解质紊乱、对症治疗等治疗。试验组在此基础上,静脉滴注血栓通注射液5 m L,溶于5%葡萄糖溶液250 m L,每日1次,持续14 d。比较2组患者治疗前、治疗7,14 d后疼痛评分、血氧饱和度变化和神经功能缺损程度评分;根据患者病情分为Ⅰ、Ⅱ、Ⅲ级,比较各级患者呼吸机使用时间、止痛药使用时间及住院时间。结果治疗7,14 d后,试验组的疼痛视觉模拟评分（VAS）分别为（2.33±0.51）,（1.20±0.38）分,对照组的VAS分别为（7.05±1.39）,（2.81±0.40）分;试验组神经功能缺损程度评分量表（NDS）评分分别为（10.70±2.99）,（8.06±3.38）分,对照组的NDS评分分别为（15.84±4.62）,（11.29±2.58）分,差异有统计学意义（P〈0.05）。治疗7,14 d后,试验组的动脉血氧饱和度（SpO_2）分别为（90.36±3.55）%,（95.52±4.07）%;对照组的Sp O2分别为（89.81±3.42）%,（94.71±3.96）%,2组与治疗前相比,差异均有统计学意义（均P〈0.05）。试验组Ⅰ、Ⅱ、Ⅲ级患者呼吸机使用时间分别为0,（1.13±0.96）,（4.02±3.70）d;对照组Ⅰ、Ⅱ、Ⅲ级患者呼吸机使用时间分别为0,（4.59±3.05）,（7.96±6.13）d;试验组Ⅰ、Ⅱ、Ⅲ级患者止痛药使用时间分别为（2.09±0.58）,（4.71±0.83）,（7.09±1.25）d,对照组Ⅰ、Ⅱ、Ⅲ级患者止痛药使用时间分别为（4.31±1.07）,（8.20±3.55）,（13.26±5.81）d;试验组Ⅰ、Ⅱ、Ⅲ级患者住院时间分别为（10.69±3.75）,（15.36±8.22）,（18.31±5.07）d,对照组Ⅰ、Ⅱ、Ⅲ级患者住院时间分别为（17.26±3.58）,（19.39±5.42）,（30.05±2.44）d,2组差异有统计学意义（P〈0.05）。2组均未发生药物不良反应。结论血栓通能够

英文摘要：

Objective To analyze the clinical effect of Xueshuantong injection in the treatment of patients with intracranial trauma combined with multiple rib fractures.Methods A total of 66 cases of cranial trauma combined with multiple rib fractures were randomly divided into treatment group and control group,33 cases in each group.Control group was treated with surgery correction and continuous oxygen inhalation,lowering intracranial pressure,neurotrophic support,the correction of water and electrolyte imbalance,symptomatic therapy and other treatments.Treatment group was intravenous given Xueshuantong 5 m L ＋ 5% glucose 250 m L,qd on the basis of control group.The course of the treatment was 14 d.The pain scores neurological function scores,and changes of oxygen saturation（Sp O2） were observed in two groups.The patients were divided into Ⅰ,Ⅱ,Ⅲ grade depends on their disease degree,the time of using breathing machine,use of analgesics,and hospital stay time of the two groups were observed.Results After 7 d treatment,the visual analogue scale（VAS） in treatment group was 2.33 ± 0.51,and was 7.05 ± 1.39 in control group;the nerve function defect score（NDS） in treatment group was 10.70 ± 2.99,and was 15.84 ± 4.62 in control group（P 0.05）.After 14 d treatment,the VAS in treatment group was 1.20 ± 0.38,and was 2.81 ± 0.40 in control group;the NDS in treatment group was 8.06 ± 3.38,and was 11.29 ± 2.58 in control group（P 0.05）.After7,14 d treatment,the Sp O2were（90.36 ± 3.55） %,（95.52 ± 4.07） % in treatment group,and were（89.81 ± 3.42） %,（94.71 ± 3.96） % in control group,had significant difference with before treatment（P 0.05）.The time of using breathing machine of Ⅰ,Ⅱ,Ⅲ grand patients were 0,（1.13 ± 0.96）,（4.02 ± 3.70） d;and were0,（4.59 ± 3.05）,（7.96 ± 6.13） d in control group.The time of using analgesics in treatment group were（2.09 ± 0.58）,（4.71 ± 0.83）,（7.09 ± 1.25） d,and were（4.31 ± 1.07）,（8.20 ± 3.55）,（13.26