中文摘要：

在这份报纸，控制尺寸并且标记 RhB 的 surface-functionalized 和 Cyclosporin A (CsA ) 装载了聚苯乙烯(PS ) nanospheres 成功地经由 miniemulsion 聚合被综合。从蛋白质吸附，血相容性，房间相容性和房间穿透性的木钉 functionalized PS nanospheres 的生物物理的性质与高 biocompatibility 显示出 nanoparticles。这些结果显示那个木钉修改了 PS nanospheres 作为低尺寸分发(0.164 ) 显示出突出的性质，高封装效率(98.3%) ，长重新石灰化时间(50% 比积极控制) ，低溶血比率(3.19%) 和高房间生存能力(95.3%) 。这个工作能为 CsA 被用作一个好药交货系统。

英文摘要：

In this paper, size-controlled and surface-functionalized RhB-labeled and Cyclosporin A （CsA）-loaded polysty- rene （PS） nanospheres were successfully synthesized via miniemulsion polymerization. The biophysical properties of PEG functionalized PS nanospheres from protein adsorption, blood compatibility, cell compatibility and cell penetrability showed the nanoparticles with high biocompatibility. These results indicated that PEG modified PS nanospheres showed outstanding properties as low size distribution （0.164）, high encapsulation efficiency （98.3%）, long re-calcification time （50% than positive control）, low hemolysis ratio （3.19%） and high cell viability （95.3%）. This work could be used as a good drug delivery system for CsA.