中文摘要：

目的分析急性百草枯中毒患者早期并发症的特点并研究哪些并发症可影响中毒患者的预后。方法对南京军区南京总医院急救医学科2005-01～2011—12收治的87例百草枯急性中毒患者的资料进行回顾分析，在患者服毒一周内采集其病历资料，分析患者出现的各种并发症，并通过四格表∥检验分析中毒死亡组患者与中毒存活组患者之间并发症发生率的统计学差别。结果急性百草枯中毒患者早期的并发症发生率最多的依次为凝血功能障碍、呼吸系统功能损害、胰腺功能损害、肾功能损害、肝功能损害、肌肉损害以及胃肠道出血。而其中肝功能损害、凝血功能障碍、呼吸功能损害、胰腺功能损害、肌肉损害这5项并发症在中毒死亡组患者和中毒存活组患者比较差异有统计学意义（P〈0．05）。结论临床医师应对急性百草枯中毒患者的早期并发症予以关注，预防并治疗服毒患者的肝功能损害、凝血功能障碍、呼吸功能损害、胰腺功能损害、肌肉损害并发症可能对改善患者预后有帮助。

英文摘要：

Objective To analyze the characteristics of early complications in the patients with acute paraquat poisoning and to find out what complications can affect the prognosis of poisoned patients. Methods 87 cases of acute paraquat poisoning patients from Emergency Medicine Department of Nanjing General Hospital from January 2005 to December 2011 were analyzed retrospectively. We collected the medical records of patients with paraquat poisoning within a week in order to analyze various concurrency diseases of patients, and statistical difference in complications rate was analyzed between the dead of poisoning and the survivals of poisoning by X2 test of fourfold table. Results We found the highest incidence of early complications in patients with acute paraquat poisoning was coagulation disorders, respiratory dysfunction, pancreatic dysfunction, renal dysfunction, liver dysfunction, muscle dysfunction, and gastrointestinal bleeding. Liver dysfunction, coagulation disorders, respiratory dysfunction, pancreatic dysfunction and muscle dysfunction had significantly statistical differences in the dead of poisoning and the survivals of poisoning （ P 〈 0. 05 ）. Conclusion Clinicians should be concerned about early complications in patients with acute paraquat poisoning, prevention and treatment of paraquat poisoning in the patients with impaired liver function, coagulation disorders, respiratory dysfunction, pancreatic dysfunction and muscle dysfunction complications may help the clinicians improve the prognosis.