作为一个吸引人的学科交差的研究领域,房间和分子的 biomechanics 一般来说在力学的优势并且 biomechanics 特别地。它有潜力在组织提供怎么强迫的量的理解和变丑,细胞、分子的层次影响人的健康和疾病。在这篇文章,我们在房间和分子的 biomechanics 考察最近的进展,检验可得到的计算、试验性的工具,并且讨论包括在 mechanotransduction,房间变丑和组成的行为的蛋白质变丑的重要问题,房间粘附和移植,和联系模型和理论。在房间和分子的 biomechanics 的机会和挑战也被讨论。我们希望提供读者,并且在应用力学社区刺激更宽广的兴趣这个领域的当前的地位的一幅清楚的图画。
As an intriguing interdisciplinary research field, cell and molecular biomechanics is at the cutting edge of mechanics in general and biomechanics in particular. It has the potential to provide a quantitative understanding of how forces and deformation at tissue, cellular and molecular levels affect human health and disease. In this article, we review the recent advances in cell and molecular biomechanics, examine the available computational and experimental tools, and discuss important issues including protein deformation in mechanotransduction, cell deformation and constitutive behavior, cell adhesion and migration, and the associated models and theories. The opportunities and challenges in cell and molecular biomechanics are also discussed. We hope to provide readers a clear picture of the current status of this field, and to stimulate a broader interest in the applied mechanics community.