中文摘要：

研究黔产野生水芹（后简称水芹）天然药物化学成分及水芹提取物对链脲佐菌素（STZ）诱导的糖尿小鼠降血糖作用。应用天然药物化学成分单项预试验方法检测水芹化学成分类型,分光光度法测定总酚酸、总黄酮、总糖含量。用STZ建立小鼠糖尿模型,二甲双胍做阳性对照,水芹醇提物灌胃,检测血糖。结果表明,水芹含酚类、黄酮类、糖类、生物碱等多种活性物质,总酚酸、总黄酮、总糖含量较高;水芹醇提物具有一定的降血糖作用,高剂量组血糖均值从27.6降至17.7。黔产水芹具有一定的研究开发价值。

英文摘要：

The chemical components of Oenanthe javanica from Guizhou and the hypoglycemic effect of its extracts on the diabetic mice induced by streptozotocin（STZ）was investigated in this paper.The chemical composition type in the wild O.javanica was detected in a single prediction experiment by using various chemical components of natural medicine.The total phenolic acids,flavonoids and sugar of O.javanica were determined by spectrophotometry.Diabetic mice model was established by STZ,and metformin was used as a positive control,the extracts from O.javanica was fed,blood glucose was measured.The results showed that O.javanica contained phenols,flavonoids,alkaloids and other active ingredients,and the total phenolic acids,flavonoids and sugar of O.javanica were found higher than other kinds of compounds.The extract from O.javanicashowed a certain hypoglycemic activity,and according to the data,decreasing blood glucose from 27.6to 17.7.Thus O.javanicafrom Guizhou contains a variety of natural drug chemical composition,showing a certain hypoglycemic effect,and it was valuable to research and explore it.