欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
人类白细胞抗原（human leucocyte antigen,HLA）复合体是人体中基因多态性最高的基因复合体,其多态性与疾病遗传易感性显著相关。人类白细胞抗原-F（human leucocyte antigen-F,HLA-F）属于非经典HLA I类分子中的一员,与HLA-E、-G在结构上十分相似,具有有限的多态性。近年来多数学者聚焦于HLA-F基因转录及分子表达调控、HLA-F表达与临床相关性及HLA-F抗体研制,且取得了重要成果。就HLA-F的研究进展作一综述。
英文摘要：
Human leukocyte antigen complex with the highest gene polymorphisms in human,is significantly associated with genetic susceptibility to diseases.Human leukocyte antigen-F belongs to the non-classical HLA I molecules.HLA-F,HLA-E and HLA-G have a similar structure and a limited polymorphism.In recent years,transcription regulation of HLA-F,expression regulation of HLA-F in cell surface,clinical relevance of HLA-F and the preparation of anti-HLA-F,are widely studied and have achieved important results.In the present review,the research advances on HLA-F are discussed.
同期刊论文项目
同项目期刊论文
Human leukocyte antigen-G expression is associated with a poor prognosis in patients with esophageal
Elevation of plasma soluble human leukocyte antigen-G in patients with chronic hepatitis C virus inf
Alteration of HLA-F and HLA I antigen expression in the tumor is associated with survival in patient
Induction of cell surface human leukocyte antigen-G expression in pandemic H1N1 2009 and seasonal H1
HLA-G expression is associated with metastasis and poor survival in the Balb/c nu/nu murine tumor mo
Human leukocyte antigen-G (HLA-G) expression in cervical cancer lesions is associated with disease p
Plasma soluble human leukocyte antigen-G expression is a potential clinical biomarker in patients wi
Multiple steps of HLA-G in ovarian carcinoma metastasis: alter NK cytotoxicity and induce matrix met
期刊信息
位置：