中文摘要：

炎症是最基本的病理变化之一，包括感染性与非感染性炎症。在炎症发生发展过程中，细胞因子起着重要的作用，主要表现为促炎和抗炎细胞因子之间相互促进相互制约作用，前者主要有肿瘤坏死因子-α、干扰素-γ、白细胞介素（IL）-2、IL-6及IL-17、IL-23等，后者主要包括IL-4、IL-10、IL-13、转化生长因子-β等，两者的动态变化决定炎症的发展及结局。研究炎症尤其是感染性炎症中的炎性细胞因子对可能取得彻底治愈炎性疾病的突破有重要意义。本文对在细菌感染中起重要作用的主要促炎与抗炎细胞因子作一综述。

英文摘要：

Inflammation is one of basic pathological changes, including infective and noninfective inflammation. Inflammatory cytokines play an important role in the process of inflammation, which is the interaction be- tween pro-inflammatory cytokines like tumor necrosis factor-or, interferon-γ, interleukin（IL）-2, IL-6, IL-17, IL-23 and anti-inflammatory cytokines such as IL-4, IL-10, IL-13, transforming growth factor（ TGF） -β. The dynamic change between pro-cytokines and anti-cytokines determines the ending and outcome of inflammation. Research on cytokines in inflammation especially in infective inflammation is meaningful, as it may be the next breakthrough of thorough cure in inflammatory disease. This article reviews the researches on the key cytokines in bacterial infection.