中文摘要：

目的探讨不可触及乳腺癌的诊断和治疗。方法回顾分析26例不可触及乳腺癌的诊断、术前定位和手术治疗。结果26例26个病灶均经超声和乳腺钼靶摄片发现，经超声或钼靶导引下导丝定位行局部扩大切除术。其中14个病灶为导管原位癌，9个病灶为导管原位癌伴微浸润，3个病灶为浸润性导管癌。结论超声和乳腺钼靶摄片相结合可提高不可触及乳腺癌的发现率，超声或钼靶导引下行病灶局部扩大切除可缩短手术时间，避免再次手术时过多地切除乳腺组织，保留了乳房的外形美观。

英文摘要：

Objective To evaluate the diagnosis and surgical management of non-palpable breast cancer （NPBC）. Methods Diagnosis, preoperative localization and surgical management of 26 cases of NPBC were an- alyzed retrospectively. Results All the 26 lesions were found by ultrasound or mammography. Local-extensive excision was performed under preoperative ultrasound-guided or radio-guided wire localization. Of the 26 lesions, 14 were ductal carcinoma in situ （DCIS） , 9 were DCIS with micro-invasion and 3 were invasive duetal carcino- ma. Conclusions Combination of ultrasound and mammography improves the discovery rate of NPBC. Local-ex- tensive excision under preoperative ultrasound-guided or radio-guided wire localization of NPBC shortens the dura- tion of surgical procedure, avoids excessive resection of breast tissues and maintains the apperance of the breast.