胃肠道炎性肌纤维母细胞瘤(inflammatory myofibroblastic tumor,IMT)是一种特殊而少见的间叶性肿瘤,发病部位主要位于胃和回盲部,常见于学龄前儿童及青少年,女性多发,临床表现无特异,术前诊断困难,确诊需依据术后病理及免疫组织化学,一般预后良好,偶有复发。本文就胃肠道IMT的临床表现、病理检查及免疫组织化学特点、诊断及鉴别诊断、治疗及预后等作一综述。
Inflammatory myofibroblastic tumor(IMT) of gastrointestinal tract is a peculiar and rare kind of tumors from mesenchymal tissue.It mainly occurs in stomach and ileocecum and is more likely associated with preschool children as well as youngsters,showing slight female predominance.The clinical manifestations of gastrointestinal IMT are not specific so that preoperative diagnosis is very difficult.Diagnosis depends on the pathological and histological examinations and usually has favorable prognosis,occasional relapse may happen however.This review discussed the clinicopathological and immunohistochemical characteristics,diagnosis and differential diagnosis,treatment and prognosis of gastrointestinal IMT.