中文摘要：

这研究的目的是在三个直角的方向在明显的水平，以及织物水平学习腰部的脊椎的 trabecular 骨头的年龄相关的改编。90 个 trabecular 标本在二个年龄组从六具男死尸的六正常 L4 脊椎的身体被获得，三变老 62 年并且三变老 69 年，并且用高分辨率的微计算断层摄影术(micro-CT ) 被扫描系统，然后变换成微有限的元素模型做微有限的元素分析。当在纵的方向独立压缩了时，在明显的僵硬和骨头体积部分之间的关系，和织物水平 von 协定为每个 trabecular 标本强调分发，中间的侧面、前面的以后的方向(横向的方向) 在二之间被发源并且比较年龄组。结果证明在明显的水平，从 69 年的组的 trabecular 骨头在所有三个方向，并且在两个年龄组相对他们的体积部分有更生硬的骨头结构，在骨头体积部分的变化能比横向的方向在纵的方向在明显的僵硬解释更多的变化；在织物水平，老化在所有三个方向为压缩在织物 von 协定压力分布上有小效果。现在的学习的新奇是它从二个不同层次在年龄和中国男腰部的脊椎的 trabecular 骨头的方向相关的改编提供了量的评价：在明显的水平的僵硬和在织物水平的压力分发。它可以帮助理解失败机制和在年长的个人为骨折风险的预防与老化和方向联系的脊椎的身体的骨折风险。

英文摘要：

The objective of this study was to study the age-related adaptation of lumbar vertebral trabecular bone at the apparent level, as well as the tissue level in three orthogonal directions. Ninety trabecular specimens were obtained from six normal L4 vertebral bodies of six male cadavers in two age groups, three aged 62 years and three aged 69 years, and were scanned using a high-resolution micro-computed tomography （micro-CT） system, then converted to micro- finite element models to do micro-finite element analyses. The relationship between apparent stiffness and bone volume fraction, and the tissue level yon Mises stress distribution for each trabecular specimen when compressed separately in the longitudinal direction, medial-lateral and anterior-posterior directions （transverse directions） were derived and compared between two age groups. The results showed that at the apparent level, trabecular bones from 69-year group had stiffer bone structure relative to their volume fractions in all three directions, and in both age groups, changes in bone volume fraction could explain more variations in apparent stiffness in the longitudinal direction than the transverse directions; at the tissue level, aging had little effect on the tissue von Mises stress distributions for the compressions in all the three directions. The novelty of the present study was that it provided quantitative assessments on the age and direction- related adaptation of Chinese male lumbar vertebral trabecular bone from two different levels： stiffness at the apparent level and stress distribution at the tissue level. It may help to understand the failure mechanisms and fracture risks of vertebral body associated with aging and direction for the prevention of fracture risks in elder individuals.