介入治疗是介于外科和内科治疗之间的新兴治疗方法,其中用于胆管、食管和气管等官腔的支架属于非血管介入治疗。非血管可降解支架与官腔具有良好的生物相容性,并且支架置人人体后,可以在一定时间内降解,转化为对人体无害的小分子排除体外。本文综述了介入治疗用非血管可降解支架的研究进展,重点介绍了非血管可降解支架的材料选择,外形设计,支架工艺(包括支架成型,覆膜改性,载药处理),性能测试(包括物理性能,力学性能,生物相容性,降解性能等)及临床应用进展。
Interventional therapy is the new treatment between surgical and medical treatment, and the non-vascular interventional treatment includes bile duct, esophagus, trachea and other bureaucratic. Non-vascular biodegradable stents have great biocompatible with bureaucratic, and they will degrade into harmless small molecules out of the body during a certain time after stents are replanted in body. In this paper, the research progress of non-vascular biodegradable stents were reviewed, and material selection, shape design, stent process (including stent molding, film modification and drug treatment), Performance tests (including physical properties, mechanical properties, biocompatibility, degradation properties, etc. ) and progress in clinical application of non- vascular biodegradable stents were mainly introduced.