中文摘要：

微小单胞菌是一种革兰阳性厌氧球菌，广泛存在于根尖周炎感染根管中。16SrRNA测序法显示，微小单胞菌分别与具核梭杆菌、中间普雷沃菌和厌氧消化链球菌之间具有相关性，其检出率次于具核梭杆菌。微小单胞菌具有明显的蛋白水解酶活性，可以通过刺激巨噬细胞释放某些炎症递质引发或参与炎症反应，特别是形成持续性的炎症；可以利用谷胱甘肽产生挥发性的硫化物，即根管内恶臭可能与之有关。本文就微小单胞菌在感染根管中的分布、微小单胞菌与其他优势菌间的相关性、微小单胞菌的致病性等研究进展作一综述。

英文摘要：

Parvimonas micra（P.micra） is a gram-positive anaerobic coccus that is often found in infected root canals of periapical periodontitis. Based on 16S rRNA PCR, correlations exist between P.micra and Fusobacterium nucleatum（F. nucleatum） and Prevotella intermedia and Peptostreptcoccus anaerobius. The detection rate of P.micra after F.nucleatum indicates that the former has obvious proteolytic activity. It can initiate or participate in inflammation by stimulating the release of some inflammatory mediators in macrophages, especially the formation of persistent inflammation. P.micra can use glutathione to produce volatile sulfur compounds, which may be related to root canal stench. This article summarizes research on the distribution of P.micra in the infected root canal, correlation between P.micra, and other dominant bacteria, and pathogenicity of P.micra.