中文摘要：

采用溶胶-凝胶法制备氧化锌纳米材料并考察了其抗菌性能。研究发现，通过调控醋酸锌-无水乙醇-氢氧化钠反应体系的反应温度、反应时间、反应物浓度以及反应体系中的水含量可以控制纳米ZnO的粒径分布；以金黄色葡萄球菌和大肠杆菌作为革兰氏阳性菌和革兰氏阴性菌的代表，用抑菌圈法考察了材料的抗菌性能，结果表明，溶胶-凝胶法合成的ZnO纳米材料抑菌效果明显优于相应的水热法产物和市售产品，且与其粒径分布密切相关；在实验条件下，ZnO材料对大肠杆菌和金黄色葡萄球菌的抑制性能随ZnO纳米材料的粒径增大在5nm左右出现-个极值，材料的粒径小于或大于5nm，其抗菌效果均变差。

英文摘要：

The synthesis of ZnO nanomaterials with sol-gel method and its antibacterial propertieshave been investigated systematically. The reaction system composing of Zn（CH3COO）2-CH3 CH2OH-NaOH was employed for the fabrication of nano ZnO. Ithas been found that the size of ZnO particles can be controlled effectively by tailoring reaction temperature,reacting time,concentration of reactant and water content in the system. The antimicrobial capacity of the ZnO prepared with sol-gel method is much better than the ZnO materials prepared withhydrothermal method and the commercial ZnO materials. The antibacterial activities of ZnO is size-dependent,and increase significantly with the decreasing of particle size when the ZnO nanoparticles bigger than 5nm, however,opposite trend appears when the ZnO nanoparticles smaller than 5nm.