中文摘要：

药物基因组学在新药开发的多个阶段可发挥重要作用。研究者可借助基因组信息更好地发现新药的作用靶点及其作用机制,药物基因组及其相关技术的发展帮助研究者在新药开发的临床前研究阶段淘汰化学性质不良的化合物,还可指导新药开发的临床试验设计以增加药物有效性和安全性,同时降低开发所需的时间和成本。

英文摘要：

Pharmacogenomics has the potential to impact on the drug discovery and development process at many stages.Pharmacogenomic information helps researchers in drug discovery to better identify drug targets and the mechanisms of action of investigational New Chemical Entity （NCEs）.Pharmacogenomics-related technology facilitates the removing of unfavorable products at preclinical stages of drug development.It also could guide companies in designing clinical trials that would more definitively confirm drug efficacy,consecutively decreasing the time,costs,and risks of drug development as well.