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中文摘要：
质子核磁共振（^1H NMR）谱在肿瘤研究中有着广泛的用途，活体定域^1H NMR谱、原位活体组织萃取液的高分辨^1H NMR谱、原位活体组织的高分辨魔角旋转^1H NMR谱和生物体液的离体高分辨^1H NMR谱各有优势，互为补充，为肿瘤的研究提供有价值的信息。基于^1H NMR的代谢组学将NMR检测和多变量数据分析有机地结合起来，这种新技术在肿瘤的早期诊断、肿瘤发展和预后监测等方面具有巨大的应用潜力和广阔的应用前景。
英文摘要：
^1H nuclear magnetic resonance （^1H NMR） spectroscopy has found widespread applications in tumour studies. Several complementary NMR techniques have provided valuable information concerning tumours, including in vivo localized ^1H NMR spectroscopy, ex vivo high-resolution ^1H NMR spectroscopy of extracts of intact tissue biopsy samples, high-resolution magic angle spinning ^1H NMR spectroscopy of intact tissue biopsy samples, and in vitro high-resolution ^1H NMR spectroscopy of body fluids. On the basis of the combination Of NMR measurements with multivariate data analysis, ^1H NMR-based metabonomics has become a promisingly novel approach in the studies of tumour early diagnosis, processes and prognosis estimate.
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