中文摘要：

目的 观察早期应用阿托伐他汀治疗进展性缺血性脑卒中的临床疗效.方法 将60例进展性缺血性脑卒中患者随机分为治疗组与对照组各30例,对照组仅用常规治疗方法,治疗组在常规治疗方法的基础上加用阿托伐他汀40mg,每晚1次,疗程为14天,两组均于治疗前后测定血脂、CRP,并于治疗前、治疗后3、7、14、21d进行神经功能缺损评分.结果 治疗后7、14、21d神经功能缺损评分明显下降,与对照组比较,差异有显著性（P＜0.05）;治疗后的总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、CRP亦较治疗前明显降低（P＜0.05）,且无不良反应.结论 早期应用阿托伐他汀治疗进展性缺血性脑卒中疗效较好,且无不良反应,可在临床推广应用.

英文摘要：

Objective To explore the effect of atorvastatin on treatment progressive stroke.Methods 60 patients with progressive stroke were randomly divided into therapy group （30 cases） and control group （30 cases）.The therapy group was treated with basic treatment and Atorvstatin （40mg/d for 14 days）.Lipid profiles,CRP and nervous function evaluation were checked up and the efficacy was analyzed.Results The situation of nervous function was remarkably in 7 ／14 and 21 days after treatment in treatment group as compared with what in control group（P〈0.05）.TC,LDL-C and CRP were decreased significantly（P〈0.05）.No side-effect was found in the groups.Conclusion A good efficacy is obtained in treating progressive stroke with atoprvastatin.