中文摘要：

通过可逆加成-断裂链转移（RAFT）自由基反应，在球形硅胶表面制备了分子印迹纳米膜.茶碱吸附实验显示，与对照组的杂化球形硅胶相比，分子印迹纳米膜杂化球形硅胶对茶碱具有更高的吸附结合能力.利用RAFT所具有的活性/可控的特点，通过改变实验条件控制分子印迹纳米膜在硅胶表面的生长，可以得到较厚的分子印迹纳米膜以获得较好的吸附量，也可以得到较薄的分子印迹纳米膜以获得较好的吸附效率.

英文摘要：

In this study, molecularly imprinted polymer （MIP） nano- films for theophylline were prepared on the surface of silica microspheres through reversible addition - fragmentation chain transfer （RAFT） polymerization. The theophylline binding analysis showed that, compared with the control polymer nano- films hybridizing silica microspheres, the MIP nano- films hybridizing silica microspheres had higher affinity for theophylline. Utilizing the controllable nature of RAFT, we could control the growth of MIP nano - films on the silica microspheres. Thus it is possible to tailor the resulting microspheres to have high capacities by growing thicker MIP nano -films or higher binding efficiency by growing thinner MIP nano -films.