目的探讨蒙古族人群中血清尿酸水平与代谢综合征及C-反应蛋白的关系。方法选取内蒙古自治区某地14个行政村的蒙古族居民1 430人,分别测量血压、身高、体重、腰围、臀围等,检测研究对象的空腹血糖、血脂各项、C-反应蛋白、血清尿酸、肌苷等指标。应用SPSS 13.0软件进行分析。结果该人群中MS的患病率为17%;MS人群组中血清UA水平为147.22 mmol/L,显著高于非MS人群的121.77 mmol/L;在蒙古族女性居民中,MS随着血清UA水平的增高而增高。在调整年龄、性别、肌苷、TG、HDL和LDL后,血清UA水平与CRP之间没有显著性相关。结论在蒙古族女性人群中,血清尿酸水平与MS显著相关,但未见其与CRP存在关联。
Objectives To examine the association of serum uric acid level with metabolic syndrome (MS) and C-reactive protein in Chinese Mongolian adults. Methods A total of 1 430 subjects aged 30 or older were recruited including 594 males and 836 females. Serum UA was measured with a colorimetric method. Multivariate regression analysis was used to detect the potential risk factors of UA; Logistic regression was used to analyze the relationship between UA quartiles and MS. Results Approximately 17 % subjects had MS. Serum UA level in MS group was 147.22 mmol/L higher than 121. 77 mmol/L in non-MS group. The risk of MS increased with the rising UA level, especially in female Chinese Mongolians. Serum UA was not correlated with Iog-CRP after adjustment for age, gender, creatine, triglyceride, total, LDL and HDL-cholesterol. Conclusions Serum UA level is significantly correlated with MS, especially in Chinese Mongolian females, but no correlation has been found between serum UA level and Iog-CRP in Chinese Mongolians after adjustment for risk factors.