中文摘要：

酶催化剂是功能强大的催化剂之一，它们能够在体内温和的条件下催化各种生物反应。通常酶的催化功能表现在强的催化活性以及控制产物立体专一选择性方面，比如酶在生物体系内催化阳离子引发的多烯环化反应来合成胆固醇，用于制备各种萜类化合物和类固醇的过程．酶的这些特性吸引了化学家们强烈的研究兴趣，发展了仿生化学来模拟生物化学的各种转化．本文简单介绍了目前仿生阳离子引发的多烯环化反应的研究成果；总结了我们课题组在过去几年里在这一领域研究的贡献．

英文摘要：

Enzyme is one of the most powerful catalysts. It can catalyse various biochemical reactions very effectively in vivo under very mild conditions. In most cases, it exhibits high catalytic activity and results in products with perfect optical purities. One of such processes is the enzyme-catalysed synthesis of cholesterol in the biological systems for the synthesis of various terpenoids or steroids via the cationic nolvene cyclization reaction. Therefore, there has been a strong interest among chemists in developing biomimetic versions of many of these biochemical transformations. This paper briefly describes the currenl research status of this field and our group＇s research contribution in this area.