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中文摘要：
组胺是一种单胺类神经递质和活性信号分子,其通过与组胺受体结合,在多种生理及病理过程中发挥重要作用。目前已知的组胺受体有4型,H1-4,均属于G蛋白偶联受体家族。[1]组胺受体广泛表达于中枢神经系统及外周组织,参与调解过敏反应、胃酸分泌、炎症反应及中枢神经系统兴奋性等。以组胺受体为作用靶点的药物被用于抗过敏、抗胃酸、止晕、止吐及镇静等[2]。
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