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放线菌YIM48789发酵液中化学成分的研究
  • 期刊名称：云南大学学报(自然科学版)
  • 时间：2010.7.7
  • 页码：460-462
  • 分类：Q939.9[生物学—微生物学]
  • 作者机构：[1]云南大学化学科学与工程学院教育部自然资源药物化学重点实验室,云南昆明650091, [2]云南大学云南省微生物研究所,云南昆明650091
  • 相关基金：NSFC-云南联合基金项目资助（U0932601）
  • 相关项目：4种云南特境放线菌抗肿瘤新活性成分的发现
作者： 刘超|杨亚滨|杨雪琼|杨志|曹艳茹|陈云|赵立兴|丁中涛|
关键词： 放线菌, 化学成分, 发酵, 柱色谱, 分离, Actinomycete, chemical constituents, ferment, column chromatography, separation
中文摘要：

对放线菌YIM48789的发酵物进行化学成分研究,采用柱色谱方法进行分离纯化,从中分离得到6个化合物,根据光谱数据鉴定为1-O-乙酰基-甘露醇（1）、环（脯-丝）（2）、尿嘧啶核苷（3）、2’-脱氧尿嘧啶核苷（4）、腺嘌呤核苷（5）、胡萝卜甙（6）.化合物1首次从天然物中分离得到,化合物2～6均首次从该放线菌的发酵物中分离得到.

英文摘要：

To study the chemical constituents from fermentation broth of actinomycete YIM48789.Six compounds were isolated by column chromatography.Their structures were elucidated based on spectral analysis and determined as 1-O-acetyl-mannitol （1）,cyclo（Pro-Ser）（2）,uridine（3）,2’-deoxyuridine（4）,adenosine（5）,daucosterol （6）.Compound 1 was firstly isolated from natural sources,compounds 2—6 have been isolated from this actinomycete for the first time.

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4种云南特境放线菌抗肿瘤新活性成分的发现
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