中文摘要：

目的：研究丰富环境对小鼠吗啡成瘾性的影响。方法：40只6小鼠随机分为丰富环境组（n=20）和普通环境组（n=20），利用行为敏化和条件性位置偏爱实验评价动物的精神依赖性。结果：丰富环境降低小鼠吗啡（10mg·kg^-1）行为敏化的形成，阻断吗啡（5mg·kg^-1）诱导的条件性位置偏爱的建立。结论：丰富环境可能对吗啡的精神依赖性具有干预作用。

英文摘要：

Objective： To investigate the effects of enriched environment （EE） on morphine addiction. Methods： Forty male mice were divided into enriched environment group （n = 20） and standard environment group（n = 20）. Behavioral sensitization and conditioned place preference （CPP） experiments were used to measure the opiate psychological dependence. Results：Enriched enviromnent significantly attenuated morphine （10 mg·kg^-1） -induced behavioral sensitization in mice, and blocked morphine （5mg·kg^-1） - induced CPP. Conclusion：EE might be useful in the treatment of opiate psychological dependence.