Increased Levels of p53 and PARP-1 in EL-4 Cells Probably Related with the Immune Adaptive Response Induced by Low Dose Ionizing Radiation in vitro
- ISSN号:0254-5098
- 期刊名称:《中华放射医学与防护杂志》
- 时间:0
- 分类:Q691[生物学—生物物理学] Q-33
- 作者机构:[1]Department of Radiotherapy, China-Japan Union Hospital, Jilin University, Changchun 130033, Jilin, China, [2]Key Laboratory of Radiobiology, Ministry of Health (School of Public Health, Jilin University), Changchun 130021, Jilin, China, [3]Department of Nuclear Medicine, the First Hospital, Jilin University, Changchun 130021, Jilin, China
- 相关基金:This research was supported by the National Natural Science Foundation of China (30570546 and 30870747), the Natural Science Foundation of Jilin Province (20090458 and 201015183), the Young Teachers Innovative Foundation of Jilin University (421010043430) and the Young Scholars Research Foundation Program of China-Japan Union Hospital (2009). ACKNOWLEDGEMENTS The authors express their sincere thanks to Prof. Shu-Ping REN, Department of Toxicology, School of Public Health, Jilin University, for her strong support in the manuscript preparation. The authors declare that they have no competing interests.
作者:
GUANG-HUI CHENG[1,2], NING WU[1,2], DE-Fu JIANG[1], HONG-GUANG ZHAO[3], QIAN ZHANG[1], JIAN-FENG WANG[1,2], SHou-LIANG GONG[2,1]
关键词:
电离辐射诱导, mRNA水平, p53蛋白, PARP, 细胞凋亡, 免疫反应, 低剂量, EL, Low dose radiation (LDR), Adaptive response (AR), DNA repair
中文摘要:
These two authors contributed equally to this work.
Correspondence should be addressed to Shou-Liang GONG. E-mail: gongsl@ 163.com