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中文摘要：
目的分析当归中的主要化学成分。方法采用高效液相色谱一质谱联用的方法对当归中一些主要化学成分进行定性研究，并对当归中苯酞类化合物的质谱裂解规律进行了初步探讨。色谱柱为Hypersil ODS2（250mm×4．6mm，5μm），流动相为水（含甲酸0．5％）-乙腈（含甲酸0．5％），流速为1．0mL·min^-1，进样量为2μL。质谱的离子源为电喷雾离子源，采用正离子模式。结果初步推测出阿魏酸、9个已知的苯酞类化合物和一个未知的苯酞二聚物的衍生物。结论通过液相色谱一质谱联用分析可获得苯酞类化合物的丰富的结构信息，为这些化合物的定性提供了一种快速有效的方法，也为当归药材的质量控制提供更多科学依据。
英文摘要：
Aim To analyze the chemical components in Danggui （the roots of Angelica sinensis （Oliv.） Diel）. Methods HPLC-MS/MS was used to identify the main components in Danggui. Furthermore, the MS fragmentation regularity of the phthalides was proposed. The mobile phase of HPLC consisted of 0. 5% acetic acid in water and 0. 5% acetic acid in acetonitrile, analytical column was Hypersil ODS2 （250 mm ×4.6 mm, 5 μm）, flow rate 1.0 mL · min^-1, injected volume 2 μL. The ionization source was ESI in positive ion mode. Results Ferulic acid, nine known phthalides and one unknown phthalide derivative were tentatively identified in chromatograms based on their MS data and the comparison of their UV spectra with those published in the literatures. Conclusion The structural information of phthalides was obtained via HPLC-MS/MS, which provides an accurate and fast method to identify the phthalides and provides more scientific information for quality control of Danggui.
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