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微流控细胞芯片生命分析应用多元化

ISSN号：0253-3820
期刊名称：分析化学
时间：2012
页码：24-31
分类：O643.1[理学—物理化学;理学—化学] O657[理学—分析化学;理学—化学]
作者机构：[1]College of Science, Northwest A&F University, Yangling, Shaanxi 712100, China, [2]College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China
相关基金：The present work was supported by the National Natural Science Foundation of China （Nos. 21175107, 20975082 and 31100726）, the Ministry of Education of the People＇s Republic of China （No. NCET-08-0464）, the State Forestry Administration of the People＇s Re-public of China （No. 200904004）, the Scientific Re-search Foundation for the Returned Overseas Chinese Scholars of the State Education Ministry, and Northwest A＆F University.
相关项目：心肌缺氧/再灌注与细胞移植多功能集成微流控芯片模型构建及应用

关键词：化学反应, 微流控芯片, 平台, 小型化, 微流体装置, 化工技术, 化学实验室, 系统系统, microfluidic device, microreactor, chemical reaction

中文摘要：

作为源自微机电的系统的域的一个新使小型化的平台， Microfluidic 设备在许多学科被使用了。在化学反应的地里，基于设备的 microreactors 显示出的 microfluidic 以增加的速度和可靠性和减少的样品消费和费用造新化学技术和过程里的大诺言。这种技术也为化学合成过程的精确、高产量、自动的分析成为了一个新、有效的工具。与常规化学实验室批方法论相比， microfluidic 反应堆有很多个特征，例如高混合效率，短反应时间，高热转移系数，小反应物体积，可控制的住处时间，和高 surface-to-volume 比率，在其它之中。为化学反应在 microfluidic 设备与最近的进展结合了，这评论试图在化学合成的域里给特征的概述和 microfluidic 设备的应用程序。它也试图在化学反应的域里刺激 microfluidic 设备应用程序的开发。

英文摘要：

Microfluidic devices, as a new miniaturized platform stemming from the field of micro-electromechanical sys-tems, have been used in many disciplines. In the field of chemical reactions, microfluidic device-based microreac-tors have shown great promise in building new chemical technologies and processes with increased speed and reli- ability and reduced sample consumption and cost. This technology has also become a new and effective tool for precise, high-throughput, and automatic analysis of chemical synthesis processes. Compared with conventional chemical laboratory batch methodologies, microfluidic reactors have a number of features, such as high mixing ef- ficiency, short reaction time, high heat-transfer coefficient, small reactant volume, controllable residence time, and high surface-to-volume ratio, among others. Combined with recent advances in microfluidic devices for chemical reactions, this review aims to give an overview of the features and applications of microfluidic devices in the field of chemical synthesis. It also aims to stimulate the development of microfluidic device applications in the field of chemical reactions.