目的 探讨儿童睾丸不成熟畸胎瘤的临床特点、治疗方法及预后.方法 回顾性分析2005年1月至2015年6月我们诊治的19例儿童睾丸不成熟畸胎瘤的临床资料.年龄16 d ~ 13个月,中位年龄6个月9d.肿瘤位于左侧10例,右侧9例.18例表现为无痛性睾丸增大.病史20 d~4个月,平均1.4个月.肿瘤大小:1.5cm×1.2cm×0.5cm~6.0cm×5.0cm×4.5cm,术前17例行甲胎蛋白检查,均升高.术前行睾丸超声检查均为囊实性混合包块,有钙化.结果 8例行瘤睾切除术,11例行保留睾丸肿瘤剜除术.术后均未予化疗.15例获随访,随访时间1 ~ 10年,均无瘤存活,未见肿瘤复发及转移.结论 儿童睾丸不成熟畸胎瘤较罕见,好发于1岁内,其生物学特性为良性过程,可行保留睾丸的肿瘤剜除术,术后需密切随诊.
Objective To summarize the management of immature testicular teratomas in children.Methods The clinical data of 19 children (age between 16 days to 13 months) with immature testicular teratomas were retrospectively analyzed.There were 10 cases in left and 9 cases in right side.The main presentation was painless scrotal mass.The size of the tumor was 1.5 cm × 1.2 cm × 0.5 cm-6.0 cm × 5.0 cm × 4.5 cm.Abnormal alpha fetopmtein (AFP)concentrations were detected in 17 patients before surgery.Results Testis-sparing surgeries were done in 11 patients,and the other 8 patients underwent testicle resection because of tumor severely invading testis.Fifteen cases were followed up for 1-10 years.All of them were alive.Conclusions Immature testicular teratomas was rare and almost presenting in children younger than 1 year old.The biological behavior of immature testicular teratomas in children was benign.Testicular-sparing surgery was possible.Close follow-up should be done postoperatively.