中文摘要：

目的：探讨女性顽固性盆腔结核与细胞壁缺陷结核分枝杆菌的关系。方法：采集接受过正规抗结核治疗的女性盆腔结核患者的月经血或盆腔干酪样病灶或腹水,分离培养,滤过培养物分离L型后,对其进行药物敏感性的检测。结果：女性盆腔结核患者体内可分离出细胞壁缺陷分枝杆菌,L型结核菌对抗结核药物利福平不再敏感,但对阿米卡星、罗红霉素和环丙沙星的药物敏感性增高。结论：细胞壁缺陷导致结核分枝杆菌药物敏感性改变,可影响对盆腔结核的治疗效果。

英文摘要：

Objective： To discuss the relationship between female pelvic tuberculosis and mycobacterial cell wall- deficient forms. Methods：The L- forms separated from menstrual blood,caseous focus or ascitic fluid of femal patients with pelvic tuberculosis having received regular anti-tuberculosis treatment were detected for the drug susceptibility. Results： The L- forms were isolated from the female patients with pelvic tuberculosis. Mycobacterial L- forms were no longer sensitive to the antitubercular agents rifampin but more sensitive to amikacin,ROX and CPFX. Conclusions： Mycobacterial cell wall- deficient forms can change the drug susceptibility,affecting the therapeutic effect of pelvic tuberculosis.