关节软骨损伤后修复能力有限,组织工程为软骨疾病的治疗开辟新的途径。现从关节软骨的结构和功能、组织工程的种子细胞、支架材料、体外培养以及修复机理等方面阐述国内外在软骨组织工程领域的研究进展,并指出软骨组织工程存在和需要解决的问题。
The repair capacity of articular cartilage is limited after injury. Tissue engineering cartilage provide a challenge for the treatment of cartilage diseases. This article review the structure and function of articular cartilage, cells type,scaffold,culturing in vitro and mechanism of cartilage repair in tissue engineering, and point out the problem of existing and need solving in articular cartilage tissue engineering.