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Marine natural product des-O-methyllasiodiplodin effectively lowers the blood glucose level in db/db mice via ameliorating inflammation
  • ISSN号：1671-4083
  • 期刊名称：《中国药理学报：英文版》
  • 时间：0
  • 分类：Q959.837[生物学—动物学] U672.72[交通运输工程—船舶及航道工程;交通运输工程—船舶与海洋工程]
  • 作者机构：[1]School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China, [2]State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
  • 相关基金：We are grateful to Dr Mayumi NISHI for providing the GFP- rMR vector and Dr Gordon HAGER for the GFP-GR plasmid （pCI-nGFP-C656G）. This work was supported by the National Marine 863 Pro- gramme （grant 2011AA09070102）, the National Natural Sci- ence Foundation of China （grants 81173105 and 91213306）, the National Science and Technology Major Project （grants 2012ZX09301001-004 and 2012ZX09103101-18）, the Foundation of Chinese Academy of Sciences （grant KSCX2-EW-Q-3） and the Science Foundation of Shanghai （grant 11XD1406100）.
作者： Rong ZHOU[1], Zhong-hui LIN[2], Cheng-shi JIANG[2], Jing-xu GONG[2], Li-li CHEN[2], Yue-wei GUO[2], Xu SHEN[1,2]
关键词： 海洋天然产物, 血糖水平, DB, 小鼠, 3T3-L1细胞, HEPG2细胞, 表面等离子体共振, 分子相互作用, des-O-methyllasiodiplodin, diabetes, db/db mice, pro-inflammatory cytokine, ROS, mineralocorticoid receptor, aldosterone, blood glucose, glycosylated hemoglobin （HbAlc）
中文摘要：

E-mail lilichen@mail.shcnc.ac.cn . ywguo@mail.shcnc.ac.cn xshen@mail.shcnc.ac.cn

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期刊信息
  • 《中国药理学报：英文版》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中科院上海药物研究所
  • 主编：丁光生
  • 地址：上海市太原路294号31号楼
  • 邮编：200031
  • 邮箱：
  • 电话：021-54922821 54922822
  • 国际标准刊号：ISSN：1671-4083
  • 国内统一刊号：ISSN：31-1347/R
  • 邮发代号:4-295
  • 获奖情况:
  • 1992、1996年两届全国优秀科技期刊一等奖,1992、1996、1997年中国科协、中科院以及上海市优...,首届国家期刊奖、2000年中科院优秀期刊评比特别奖
  • 国内外数据库收录:
  • 俄罗斯文摘杂志,美国化学文摘（网络版）,英国农业与生物科学研究中心文摘,波兰哥白尼索引,荷兰文摘与引文数据库,荷兰医学文摘,美国生物医学检索系统,美国剑桥科学文摘,美国科学引文索引（扩展库）,美国生物科学数据库,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,英国食品科技文摘,中国北大核心期刊（2000版）
  • 被引量:1239