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爱普利注射剂对放牧绵羊体内外寄生虫的驱虫试验

ISSN号：1003-7950
期刊名称：《青海畜牧兽医杂志》
时间：0
分类：S853.32[农业科学—临床兽医学;农业科学—兽医学;农业科学—畜牧兽医]
作者机构：[1]青海省畜牧兽医科学院,西宁810016, [2]青海省祁连县畜牧兽医站,祁连810400
相关基金：青海省科技厅科技促进新农村计划项目（2013-N-511）; 公益性行业（农业）科研专项经费资助（201303037）

作者：蔡进忠[1], 雷萌桐[1], 李春花[1], 李剑[2], 李扎西才让[2], 孙建[1]

关键词：爱普利注射剂, 藏系绵羊, 线虫, 体外寄生虫, 驱虫, Eprinometie injection, Tibetan sheep, Nematode, Larva at Parasite stage, Expelling

中文摘要：

应用爱普利注射剂,选择自然感染线虫和体外寄生虫的1.5岁放牧藏系绵羊100只,分别按0.1、0.2、0.3 mg/kg.b w剂量皮下注射给药,同时设伊维菌素注射剂药物对照组和阳性对照组,评价驱除放牧绵羊体内线虫与体外寄生虫的效果。结果显示：爱普利注射剂0.2、0.3 mg/kg剂量对放牧绵羊消化道线虫虫卵转阴率分别为95.0%和100.0%,减少率分别为98.4%和100.0%;网尾线虫幼虫转阴率和减少率均达100.0%,原圆科线虫幼虫转阴率分别为90.0%和100.0%,减少率分别为96.1%和100.0%;对主要线虫虫卵（幼虫）的平均有效率分别达98.0%和100.0%;第7d对绵羊颚虱、足颚虱的转阴率、杀虫率均达100%;对羊蜱蝇的转阴率分别为90.0%和100.0%,杀虫率分别达92.3%和100%;均达到了高效。爱普利注射剂0.1 mg/kg剂量对线虫虫卵（幼虫）的转阴率、减少率及对体外寄生虫的杀虫率均次于0.2、0.3 mg/kg剂量组。对照药物伊维菌素注射剂0.2 mg/kg剂量消化道线虫虫卵转阴率、减少率分别为95.0%和97.8%;网尾线虫幼虫转阴率和减少率均达100.0%,原圆科线虫幼虫转阴率、减少率分别为85.0%和94.3%;第7d绵羊颚虱、足颚虱的转阴率、杀虫率均达100%;羊蜱蝇转阴率、杀虫率分别为80.0%和90%。阳性对照组线虫虫卵（幼虫）与给药前无明显变化、3种体外寄生虫感染情况较给药前略有增加。绵羊皮下注射3个剂量爱普利注射剂,未出现任何异常反应。试验证明爱普利注射剂3个剂量对藏系绵羊线虫虫卵（幼虫）、3种体外寄生虫均有效,其中0.2 mg/kg剂量驱除放牧绵羊线虫高效安全经济。

英文摘要：

To evaluate efficacy of eprinomectln against nematode, 100 sheep aged 1 which naturally infected with nematode were injected with Eprinometie agent as 0.1,0.2 and 0.3 mg/kg bw dosage in hypodermic respectively. Ivermectin tablet and positive were as conrol group. The result showed under 0.2 and 0.3 mg/kg dosage of IDSA, negative rate of nematode larva on alimentary canal reach 95.0% and 100.0% respectively while their decreasing rate were 98.4% and100.0% respectively. The negative rate and decreasing rate of Dictyecaulus larva reach 100%. The negative rate of Protostrongylus nematode larva reach 90.0% and 100% while their decreasing rate reach 96.1% and 100.0%.Under 0.1 mg/kg dosage level, negative rate, decreasing rate and expelling larva rate of nematode larva were smaller than under 0.2 and 0.3 mg/kg dosage level. There is not significant difference between 0.2mg/kg dosage of Ivermectin tablet and 0.2 mg/kg dosage of Eprinometic injection agent in negative rate , decreasing rate of nematode larva, Protostrongylus nematode larva on alimentary canal and total expelling larva rate of adult nematode and larva at parasite stage. No abnormal reaction happen when sheep was injected hypodermic at test level. Experiment proved that Eprinometie injection at 0.2 mg/kg was safe and effective in expelling larva.

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