中文摘要：

细胞膜感知低温环境信号，通过信号转导激活以CBF／DREB信号途径为主、兼与其他途径交谈和交叠所构成的信号网络，继而调控下游相应功能蛋白的表达，赋予植物低温抗性。文章重点介绍了拟南芥CBF／DREB信号传导途径的研究进展、CBF基因在高等植物中的保守性，以及构建CBF转基因抗冻植物所取得的成果，包括CBF的表达调控与作用的分子机制、影响CBF途径的一些重要蛋白和环境因子、组成性启动子以及冷诱导特异性启动子驱动CBF基因表达所获得的抗冻转基因植物的研究进展。同时，对该研究领域未来可能的发展方向进行了展望。

英文摘要：

The special receptors on the cellular membrane sense the low temperature signal and activate phosphorelation cascade reactions and CBF pathway through producing second messengers when temperature declines, which build a signaling network in the ways of crosstalk and overlap together with other pathways. This network controls eventually a great deal of downstream biological and physiological reactions. This review is focused on the recent progresses and the evolutional conservation of the CBF pathway as well as its applications in the plant gene engineering, including the multiple regulation, functional mechanism of CBF pathway; and generation of CBF transgenic tolerant freezing plants driving by both constitutive promoter CaMV35S and cold induced promoter RD29A. Meanwhile, the future prospective in this field is also discussed here.