目的:探讨整合性吞咽功能康复法对急性缺血性卒中后真性及假性球麻痹鼻饲患者的影响。方法前瞻性纳入符合诊断标准的54例患者,利用随机数表法分为整合组(31例)和对照组(23例)。对照组接受卒中常规治疗,包括脑保护治疗、改善脑循环、脱水、稳定血压、对症治疗等;整合组除常规治疗外,另接受整合性吞咽功能康复法,包括神经肌肉电刺激,同时给予吞咽反射促通术、口面舌咽功能训练等。比较两组整体及真性球麻痹与假性球麻痹(依据MRI和体征)的摄食功能,评价指标为经口摄食功能量表(FOIS)。结果(1)整合组FOIS评分(中位数4)高于对照组(中位数2),两组比较差异有统计学意义(P<0.01)。两组自身前后比较差异亦有统计学意义。(2)整合组假性球麻痹FOIS评分高于对照组(中位数分别为4、2),差异有统计学意义(P<0.01);真性球麻痹FOIS评分两组差异无统计学意义,但整合组FOIS评分高于对照组(中位数分别为4、3)。(3)整合组与对照组治疗前后FOIS差值中位数分别为2、1,整合组 FOIS升高的幅度大于对照组,差异有统计学意义(P<0.01)。结论整合性吞咽功能康复法可提高经口摄影食功能改善的程度,明显减少呛咳,经口摄食量增加,可进食种类增加;整合组患者假性球麻痹患者改善的效果更显著。
Objective To investigate the effect of integrated swallowing function rehabilitation training on nasal feeding patients with pseudobulbar palsy or bulbar palsy after acute ischemic stroke. Methods A total of 54 patients met the diagnosis criteria were enrolled prospectively. They were divided into either an integrated group (n=31)or a control group (n=23)using a random number table method. The patients of the control group received routine treatment of stroke,including brain protection therapy,improvement of cerebral circulation,dehydration,regulating blood pressure,and symptomatic treatment,etc;in addition to conventional treatment,those of the integrated group also received integrated swallowing function rehabilitation training,including neuromuscular electrical stimulation plus swallowing reflex facilitation technique,and oral facial glossopharyngeal function training,etc. The oral intake function in patients of the integration and pseudobulbar palsy or bulbar palsy (according to MRI and signs)was compared between the two groups. The evaluation index was the Functional Oral Intake Scale (FOIS)score. Results (1)The FOIS score (median 4)of the integrated group was higher than that of the control group (median 2). There was significant difference between the two groups (P<0. 01). There was also significant difference before and after comparison between the two groups. (2)The FOIS score of pseudobulbar palsy in the integrated group was higher than that of the control group (median scores 4 and 2 ). There was significant difference (P<0.01);There was no significant difference in the FOIS scores of bulbar palsy between the two groups,but the FOIS score of the integrated group was higher than that of the control group (median scores 4 and 3). (3)The median differences between the integrated group and the control group were 2 and 1 respectively. The increased amplitude of FOIS of the integrated group was higher than that of the control group. There was sign