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中性粒细胞淋巴细胞比值与急性心肌梗死的相关性研究
  • ISSN号:1672-5301
  • 期刊名称:《中国心血管病研究杂志》
  • 时间:0
  • 分类:R542.22[医药卫生—心血管疾病;医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:武汉大学人民医院心内科心血管病湖北省重点实验室,湖北省武汉市430060
  • 相关基金:国家自然科学基金项目(项目编号:81370283);国家青年科学基金项目(项目编号:81100130)
作者: 徐林, 陶波
中文摘要:

目的 评估中性粒细胞淋巴细胞比值(NLR)预测急性心肌梗死的临床价值.方法 选取在我院住院的急性心肌梗死(AMI)和冠心病患者,均行冠状动脉造影,分为AMI组和冠心病组,比较两组患者基线资料,分析中性粒细胞淋巴细胞比值与急性心肌梗死的关系.结果 ①与冠心病组相比,AMI组患者的中性粒细胞(Neu)水平(t=-10.501,P<0.01)及NLR水平(t=-10.695,P<0.01)明显升高,淋巴细胞(Lvm)水平(t=2.603,P=0.01)明显降低,差异具有统计学意义.②急性心肌梗死发生的多元Logistic回归分析示,NLR是急性心肌梗死发生的危险因素(OR=2.116,95%CI 1.313~3.411,P=0.002).③NLR取3.528作为预测患者发生急性心肌梗死的临界值时,曲线下面积0.869(95%CI 0.824~0.915),灵敏度为0.831,特异度为0.771,P<0.01.结论 NLR与急性心肌梗死有关,可以预测急性心肌梗死的发生.

英文摘要:

Objective To evaluate the clinical value of neutrophil lymphocyte ratio in acute myocardial infarction.Methods AMI and coronary heart disease were enrolled in our hospital.All patients underwent coronary angiography.The patients were divided into AMI group and coronary heart disease group.The baseline data of the two groups were compared and the relationship between ratio of neutrophil lymphocyte and acute myocardial infarction was analyzed.Results (1)Compared with the coronary heart disease group,the Neutrophils level (t=-10.501,P<0.01)and the level of PLR (t=-10.695,P<0.01) in the AMI group were significantly higher than those in the coronary heart disease group,and the Lymphocytes level was significantly decreased (t=2.603,P=0.01).(2)Multiple Logistic regression analysis of acute myocardial infarction,NLR was a risk factor for acute myocardial infarction(OR=2.116,95%CI 1.313-3.411,P=0.002).(3)NLR 3.528 as the prediction of the occurrence of acute myocardial infarction in the critical value of the curve under the area of 0.869(95%CI 0.824-0.915),the sensitivity of 0.831,specificity of 0.771,P<0.01.Conclusion NLR was associated with acute myocardial infarction and can predict the occurrence of acute myocardial infarction.

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期刊信息
  • 《中国心血管病研究杂志》
  • 中国科技核心期刊
  • 主管单位:中华人民共和国卫生和计划生育委员会
  • 主办单位:中国医师协会
  • 主编:万峰
  • 地址:北京市朝阳区西坝河南里29号
  • 邮编:100050
  • 邮箱:xxgzz@126.com
  • 电话:010-84541195
  • 国际标准刊号:ISSN:1672-5301
  • 国内统一刊号:ISSN:11-5122/R
  • 邮发代号:80-123
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:11227