目的 评估中性粒细胞淋巴细胞比值(NLR)预测急性心肌梗死的临床价值.方法 选取在我院住院的急性心肌梗死(AMI)和冠心病患者,均行冠状动脉造影,分为AMI组和冠心病组,比较两组患者基线资料,分析中性粒细胞淋巴细胞比值与急性心肌梗死的关系.结果 ①与冠心病组相比,AMI组患者的中性粒细胞(Neu)水平(t=-10.501,P<0.01)及NLR水平(t=-10.695,P<0.01)明显升高,淋巴细胞(Lvm)水平(t=2.603,P=0.01)明显降低,差异具有统计学意义.②急性心肌梗死发生的多元Logistic回归分析示,NLR是急性心肌梗死发生的危险因素(OR=2.116,95%CI 1.313~3.411,P=0.002).③NLR取3.528作为预测患者发生急性心肌梗死的临界值时,曲线下面积0.869(95%CI 0.824~0.915),灵敏度为0.831,特异度为0.771,P<0.01.结论 NLR与急性心肌梗死有关,可以预测急性心肌梗死的发生.
Objective To evaluate the clinical value of neutrophil lymphocyte ratio in acute myocardial infarction.Methods AMI and coronary heart disease were enrolled in our hospital.All patients underwent coronary angiography.The patients were divided into AMI group and coronary heart disease group.The baseline data of the two groups were compared and the relationship between ratio of neutrophil lymphocyte and acute myocardial infarction was analyzed.Results (1)Compared with the coronary heart disease group,the Neutrophils level (t=-10.501,P<0.01)and the level of PLR (t=-10.695,P<0.01) in the AMI group were significantly higher than those in the coronary heart disease group,and the Lymphocytes level was significantly decreased (t=2.603,P=0.01).(2)Multiple Logistic regression analysis of acute myocardial infarction,NLR was a risk factor for acute myocardial infarction(OR=2.116,95%CI 1.313-3.411,P=0.002).(3)NLR 3.528 as the prediction of the occurrence of acute myocardial infarction in the critical value of the curve under the area of 0.869(95%CI 0.824-0.915),the sensitivity of 0.831,specificity of 0.771,P<0.01.Conclusion NLR was associated with acute myocardial infarction and can predict the occurrence of acute myocardial infarction.