视黄醇结合蛋白4(retinol-binding proteins 4,RBP4)是由孕酮受体产生的重要蛋白质,其促进转化生长因子(TGF)的表达,参与胚胎的早期发育。此外,RBP4还具有参与VA转运等功能。RBP4基因是影响家畜繁殖性能的候选基因,现已在绵羊、猪、牛和其他家畜中进行了广泛研究。综述了家畜RBP4基因的作用和近年来国内外的相关研究进展。
Retinol-binding proteins 4 (RBP4) is an important protein produced by progesterone receptor. It stimulates the expression of TGF and involves in the early development of embryo and the transportation of VA. RBP4 gene is a candidate gene for the reproductive performance of domestic animals and is widely studies in sheep, swine and bovine. The research progress on function of RBP4 in domestic animals at home and abroad in recent years is reviewed in this paper.