目的 评估3.0 T术中MRI联合神经导航在岛叶胶质瘤显微手术中的应用价值.方法 回顾性分析采用3.0T术中MRI联合神经导航辅助手术的17例岛叶胶质瘤病人的临床资料,对切除程度及并发症进行评价.结果 通过术中MRI扫描,肿瘤次全切除7例,大部分切除10例;经进一步切除后,达肿瘤次全切除13例,大部分切除4例.经Fisher检验,应用术中MRI前后,肿瘤切除程度差异具有统计学意义(P=0.033).术后一过性失语2例,随访至术后1个月,语言功能恢复至术前水平.肢体运动障碍3例,随访1个月后,完全恢复2例,肌力3级1例.结论 术中MRI联合神经导航可最大程度地安全切除岛叶胶质瘤.
Objective To evaluate the application value of 3.0T intraoperative MRI combined with neuronavigation in resection of insular glioma. Methods Clinical data of 17 patients with insular glioma undergoing surgery assisted with 3.0T intraoperative MRI in combination with neuronavigation were analyzed retrospectively, and the resection extent and complications were evaluated. Results Subtotal tumor resection was achieved in 7 patients and partial resection in 10 by intraoperative MRI. As a result of further resection, subtotal tumor resection was achieved in 13 patients and partial resection in 4. There was a statistical significant difference in tumor resection between pre-and post-intraoperative MRI according to the Fisher test (P=0.033). Postoperative transient aphasia occurred in 2 patients and recovered to the preoperative level after 1 month in follow-up period. Limb movement disturbance occurred in 3 patients, recovered completely in 2 and recovered to grade 3 in 1 after 1 month follow-up period. Conclusion Surgery assisted by intraoperative MRI in combination with neuronavigation can maximally and safely resect insular glioma.