采用微量板半定量法研究新疆南疆地区特色中草药甘草及醉马草水煎液对表皮葡萄球菌的生长及其生物膜形成的影响。结果显示,较高浓度(15%及以上)的甘草水煎液能够通过抑制菌株的生长来影响表皮葡萄球菌生物膜的形成;而低浓度(7.5%)的醉马草水煎液在不影响菌株生长的情况下对表皮葡萄球菌生物膜的形成有抑制作用。
We explored the effects of two special Chinese herbs in the southern Xinjiang,Glycyrrhiza and Glabrous crazyweed herb,on biofilm formation by Staphylococcus epidermidis in order to generate a novel strategy for control of infections caused by Staphylococcus epidermidis,especial for dairy cow mastitis in Xinjiang.A microtiter assay was used to detect biofilm formation by Staphylococcus epidermidis in vitro.The results showed that a high concentration of 15% or above of Glycyrrhiza physic liquor inhibited cell growth and then attenuated biofilm formation by Staphylococcus epidermidis.However,a low concentration of 7.5% of Glabrous crazyweed herb liquor decreased significantly biofilm formation by Staphylococcus epidermidis without significant cell growth inhibition.