肿瘤干细胞学说的提出为肿瘤的治疗提供了新的靶点和方向。尽管已经从白血病、乳腺癌、脑肿瘤等肿瘤中初步分离鉴定出肿瘤干细胞,但是还有许多恶性肿瘤由于肿瘤干细胞表面标记尚不清楚而无法鉴定,通过侧群(side population,SP)细胞分选来初筛肿瘤干细胞,方法简便、有效,正被越来越多地应用。
The theory of tumor stem cell offers new target and orientation for tumor therapy. Although tumor stem cells have already been isolated and identified from acute myeloid leukemia, breast carcinoma and brain tumors through stem cell surface markers, many surface markers of malignant tumor stem cells are still not clear. Therefore a simple analysis of side population to preliminarily screen stem cells is more and more used.