中文摘要：

中国科学院近代物理研究所基于兰州重离子研究装置（HIRFL/HIRFL-CSR）,在被动型束流配送系统下采用二维分层适形照射治疗技术开展重离子治癌临床试验研究。为了更好地利用重离子束在肿瘤放射治疗中的生物物理优势并保障重离子临床治疗试验的顺利实施,一个初级版本的重离子治疗计划系统已经设计完成。此计划系统是针对被动型束流配送系统下的二维分层适形照射治疗方式来进行设计的。介绍了此系统的设计框架、可提供的功能以及利用宽束算法进行剂量计算在此系统中的实现。通过人体仿真体模实验证实由该治疗计划系统给出的靶区计划剂量与实测剂量的偏差在5%之内。最后讨论了设计较为完备的重离子治疗计划系统仍需解决的问题。

英文摘要：

Based on the Heavy Ion Research Facility in Lanzhou（HIRFL/HIRFL-CSR）,clinical trials of heavy ion radiotherapy are being conducted at the Institute of Modern Physics（IMP）,Chinese Academy of Sciences,where two-dimensional（2D）layer-stacking conformal irradiation method in a passive beam delivery system was applied.To make better use of the biophysical advantages of heavy ion beams and ensure success of the clinical trials,a preliminary version of heavy ion treatment planning system（TPS）has been developed at IMP.The TPS was designed in a manner to adapt to the 2D layer-stacking conformal irradiation method.The architecture and function of the TPS software and the implementation of dose calculation algorithm in the TPS were introduced in this paper.The deviation between the doses planned by the TPS and measured through an anthropomorphous phantom was verified to be less than 5%.Finally,the pending issues for developing a sophisticated treatment planning system at IMP were discussed.